C can compilers optimize function call through function calls

I have functions, which take a pointer to a struct, which are only accessed through function pointers in an array, can the compiler recognise this or do i need to make the structure volatile, to not break with optimizations?

struct data {
    bool running;

int (*functions[16])(struct data *);

struct data data = {
    .running = true;

while (data.running) {

Rand is just used as an example to say that it isnt known at compile time which function gets called.

Read more here: https://stackoverflow.com/questions/65725279/c-can-compilers-optimize-function-call-through-function-calls

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